LGD 4033 is more commonly known as Ligandrol, and it’s a member of the SARM family. This compound was discovered by a company called Ligand Pharmaceuticals, based in California, and is currently under development by a company called Viking Therapeutics.
The reason you’ve probabally heard of Ligandrol is likely due to its increasing popularity in the world of fitness, even thoght it was originally conceinved to help those suffering from osteoporosis. Many compounds
The current status falls under “Investigational New Drug” which Wikipedia defines as “…the means by which a pharmaceutical company obtains permission to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved. The FDA reviews the IND application for safety to assure that research subjects will not be subjected to unreasonable risk.”
There have been Phase 1 and Phase 2 clinical trails and thus far, they haven’t suggested any significant adverse effects, and this compound has shown positive results when it comes to increasing lean body mass.
Ligandrol in Pop Culture
This particular SARM has gotten more coverage in the media than others, due to a couple of notable athletes allegedly testing positive for it. The Florida Gators QB allegedly tested positive for it, however the University denies that claim.
In addition, Joakim Noah, an NBA player, was banned for 20 years for a positive LGD-4033 test result.
If you’re actively being tested for competition or anything else, do keep in mind that this compound can show up depending on when the test occurs.
The dose that people generally follow is 10mg for males, and 5mg for females. It’s inadvisable to exceed this common dosage, and a cycle will generally run for 8-12 weeks. It has been suggested that this compound may result in masculinisation, and that’s why lower doses are often recommended for females.
The half life is reported as roughly 24-36 hours, and it is typically taken once daily.
It is sometimes added to a stack with Ostarine and Cardarine.
What Does it do & What to Expect?
People use this compound for cutting, bulking, and for recomp. Since it was developed to help with osteoperosis and to help prevent muscle degradation, it can be useful in preserving gains, even while in a cutting or recomp phase.
Nutrition and exercise are crucial in achieving results, regardless of which additional supplements one is using. If you aren’t getting enough protein, and aren’t eating the right foods to build a better body and pack on muscle, then you aren’t setting yourself up for success.
Also, it should go without saying, but working out hard is still an essential piece of the puzzle. There are no compounds or supplements that can replace hard work, even the world’s most powerful traditional anabolic steroids require one to actually hit the gym and put in the work. There are compounds that can help the process, and set somebody up for success if they’re already putting in the work, or to help achieve even more with the same effort, but the effort is still the key. Nothing can replace that.
None the less, when you can get some of the positives of stronger and much more dangerous things like anabolic steroids, without the same risks and downsides, it’s no wonder this has become such a compelling addition to many people’s stacks.
There is a potential for minor testosterone suppression, but it pales in comparison to the test suppression found in anabolic steroids.
This is regarded as one of the stronger SARMs, it can help in a number of areas that are important to athletes and bodybuilders, like cutting, bulking, improving endurance, improving strength, and even helping with recovery. One’s genetics, and overall potential to put on muscle, along with their metabolism will all play a role in just how effective it ends up being. It’s seen as a helpful boost for somebody that is already putting in the work, rather than a be-all-end-all way to achieve easy results.