S4 which is also known as Andarine has long been believed to be the answer that researchers have been looking for.
It’s been thought to be the perfect SARM (Selective Androgen Receptor Modulator) which is capable of preventing muscle wasting and lower the risk of the benign form of prostatic hyperplasia.
And when phase 1 of the human trials were done, the results were promising. Some even said that everything was hunky dory.
Then suddenly, the trials were abandoned to favor the more effective Ostarine. Any chemical that can defeat something as potent as Andarine surely has to be something that’s dope.
But that is precisely what MK-2866 (Ostarine) is. It’s now known as one of the most effective SARMs in the market. It is even called as the ‘perfect SARM’ by bodybuilders.
Its performance is comparable to that of exogenous testosterone and in fact, many users compare its results to what can be achieved when using Anavar or EQ combined.
It also has the reputation of being the only SARM to have been tried and tested on humans many times.
But what does Ostarine have to offer for bodybuilders, athletes, and amateurs who want to go way and beyond their threshold? We’ll find out more about this compound in this article.
What Exactly is Ostarine?
MK-2866, GTx-024, Enobosarm or Ostarine is a SARM that has been researched and developed by GTx laboratories due to the potential therapeutic aid that it shows for treating the wasting of muscles caused by cancer.
And as we’ve already mentioned earlier, it’s a SARM that has been studied and researched extensively by different research agencies. Even up to this time, there still are studies being conducted by GTx about Ostarine after more than a decade and a half since it has been discovered.
That fact alone already speaks a lot about the potential therapeutic use of the compound and one day, it might even become a replacement for medicines that bring a lot of side-effects.
But without the interest that the bodybuilding community places on it, Ostarine would only be an unknown chemical even at its best.
Bodybuilders started to use it in the early 2000s after the data on the research conducted with it became public. Since then it has remained as one of the most popular Selective Androgen Receptor the world has ever seen.
It has been banned by sporting organizations like WADA back in 2008. It has been labeled as ‘S1 Anabolic Agent’ since then. Isn’t that flattering?
How Ostarine Works
Ostarine works by effectively binding with the androgen receptors that are found in the bone and muscle tissues.
These receptors are programmed to accept information on steroidal hormones like estrogen, DHT, and testosterone.
When these receptors are stimulated, Ostarine imitates the action of the body’s exogenous testosterone.
You can think of it as a mild version of testosterone cycle which does not produce DHT or estrogen-related side effects which most users dislike.
Its bioavailability also resembles that of Andarine which is excellent for any SARM. It’s a very effective SARM, to say the least!
What Are Ostarine’s Known Effects?
Almost every chemical that’s currently being tested and researched as a treatment for muscular dystrophy and muscle wasting will always find users who want to increase muscle mass at a rapid rate. And that is Ostarine’s most obvious effect! Below are some of the other effects of this compound:
Improved Bone Health:
As you age, your body will produce lower levels of testosterone which is a hormone that protects the bones. Ostarine improves bone health and strengthens it by raising bone density and thereby reducing the risk of fractures.
A 12-week clinical trial involving health but elderly subjects (120 of them to be exact) were given a low dose of Ostarine. After the test period, they were able to gain lean muscles and most of them reported positive improvement in their fitness levels. The dose given to them was only 3 mg per day. Those who are into bodybuilding usually take up to 25 mg per day and has claimed to gain up to 8 lbs. of lean and hard muscles within 12 weeks. Those results are what people mostly look for in a supplement.
Gains That Can Be Kept:
Ostarine also has a unique trait of keeping the gains that you get a more or less long lasting and even permanent in some way. There is going to be a very low loss of what has been gained within the 12-week cycle. This makes it one of the best off-steroid substance that you can use.
Ostarine has the potential of becoming a safer alternative to drugs that are meant to treat diabetes such as Metformin. It improves resistance to insulin and lowers the level of blood sugar in the body.
Better Lipid Profile:
Ostarine lowers the levels of Triglycerides and LDL. But it may also lower the levels of HDL which is known as good cholesterol. Many steroid cycles cause triglyceride levels to rise and become a major concern. If you’re on such steroid cycles, you can use Cardarine to complement and lessen the negative effects.
How is it Used?
A dose of 25 mg per day is recommended for men who are in the bulking or cutting cycle while women can use as low as 10 mg per day.
If you’re having a cycle for body recomposition, you may need to take a lower dose of about 15-20 mg per day.
Ostarine is capable of being stacked with all the other SARMs or even with anabolic steroids because of its good and well-rounded profile.
It can also be used as a PCT drug or you can take it in between cycles of steroid so you can maintain the muscles you worked so hard for.
Muscle building with the help of Ostarine usually takes 12 weeks. Minimal suppression might be present but not as severe as the effects of full-fledged PCT.
However, the lacking of data suggests that you’ll need to do PCT with Nolvadex or Clomid in order to stay on the safe side.
Also, if an extremely high dose of up to 40mg per day is used (which is not recommended), you might want to consider clubbing it with Al like Arimidex for instance especially if you have sensitivities with Estrogen-related side effects.
Known Side Effects of Ostarine
Ostarine’s side effects according to users are mostly just mild and temporary in nature. It includes low energy, headaches, back pain, and nausea.
Female users have been reporting imbalance in menstruation especially at high doses and others also suffered acne outbreaks.
Is It Worth It?
Ostarine is one of the most popular SARMs which delivers some promising results. Another strength that it has is its ability to fit into any bodybuilding program whether it’s cutting, bulking, or body recomposition and PCT cycle.
It allows the user to gain hard lean muscles that can be kept even when the cycle of using the substance gets discontinued. It also boosts energy and helps one to achieve better heart health. This results in an overall improvement in the quality of life.
It’s capable of being stacked with other SARMs and steroids but there’s one thing that you need to remember though. You should only buy SARMs like Ostarine from reputable sources.
Of course, you would surely want just trustworthy suppliers who provide real and authentic OStarine only and not some kind of liquid which contains anabolic steroids and other chemicals that can be toxic.